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Literature summary for 3.2.1.B26 extracted from

  • Haseltine, C.; Montalvo-Rodriguez, R.; Carl, A.; Bini, E.; Blum, P.
    Extragenic pleiotropic mutations that repress glycosyl hydrolase expression in the hyperthermophilic archaeon Sulfolobus solfataricus (1999), Genetics, 152, 1353-1361.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Saccharolobus solfataricus

Protein Variants

Protein Variants Comment Organism
additional information isolation of mutants with reduced expression of lacS. The mechanism of control occurs at the level of transcription. The mutations result in undetectable levels of lacS mRNA. The mechanism of reduction in lacS mRNA levels is unknown. It may result from events that act at the level of mRNA synthesis or mRNA degradation. Glycosyl hydrolase production in Sulfolobuis solfataricus requires a trans-acting factor for wild-type levels of expression. The trans-acting factor must recognize elements inherent to all target genes Saccharolobus solfataricus

Organism

Organism UniProt Comment Textmining
Saccharolobus solfataricus
-
-
-
Saccharolobus solfataricus 98/2
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-nitrophenyl beta-D-glucopyranoside + H2O
-
Saccharolobus solfataricus 4-nitrophenol + beta-D-glucose
-
?
4-nitrophenyl beta-D-glucopyranoside + H2O
-
Saccharolobus solfataricus 98/2 4-nitrophenol + beta-D-glucose
-
?

Synonyms

Synonyms Comment Organism
LACS
-
Saccharolobus solfataricus