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Literature summary for 3.2.1.96 extracted from

  • DeGasperi, R.; Li, Y.T.; Li, S.C.
    Presence of two endo-beta-N-acetylglucosaminidases in human kidney (1989), J. Biol. Chem., 264, 9329-9334.
    View publication on PubMed
Search for more literature for 3.2.1.96

Inhibitors

Inhibitors Comment Organism Structure
acetate endo-beta-N-acetylglucosaminidase 2 Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Homo sapiens 5829
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
endo-beta-N-acetylglucosaminidase 1 and 2 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(Man)6(GlcNAc)2Asn + H2O
-
 Homo sapiens (Man)6GlcNAc + GlcNAc-Asn
-
 ?
glycopeptide + H2O endo-beta-N-acetylglucosaminidase 1: high mannose-type asparaginylglycopeptide is hydrolyzed efficiently, little activity towards complex-type glycopeptides. endo-beta-N-acetylglucosaminidase 2: hydrolyzes both the high mannose-type and the complex-type oligosaccharide with chitobiosyl group at the reducing end and without the Asn Homo sapiens ?
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
3 3.5 endo-beta-N-acetylglucosaminidase 2 Homo sapiens
4.5
-
 endo-beta-N-acetylglucosaminidase 1 Homo sapiens

pH Range

pH Minimum pH Maximum Comment Organism
2.5 4.5 about 70% of maximal activity at pH 2.5 and at pH 4.5, endo-beta-N-acetylglucosaminidase 2 Homo sapiens
4.5 7 pH 4.5: about 60% of maximal activity, pH 7.0: about 50% of maximal activity, endo-beta-N-acetylglucosaminidase 1 Homo sapiens