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Literature summary for 3.2.1.52 extracted from

  • Koo, I.C.; Ohol, Y.M.; Wu, P.; Morisaki, J.H.; Cox, J.S.; Brown, E.J.
    Role for lysosomal enzyme beta-hexosaminidase in the control of mycobacteria infection (2008), Proc. Natl. Acad. Sci. USA, 105, 710-715.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.2.1.52

Localization

Localization Comment Organism GeneOntology No. Textmining

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Drosophila melanogaster HEXO2 Is important for limiting growth of Mycobacterium marinum in S2 cells. HEXO2 isoform is sufficient to control bacterial growth in S2 cells ?
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 ?
additional information Mus musculus HEXO2 Is important for limiting growth of Mycobacterium marinum in S2 cells. HEXO2 isoform is sufficient to control bacterial growth in S2 cells ?
-
 ?

Organism

Organism UniProt Comment Textmining
Drosophila melanogaster
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-
-
Mus musculus
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-
-

Source Tissue

Source Tissue Comment Organism Textmining
macrophage the importance of beta-hexosaminidase for restricting mycobacterial growth during mammalian infections is confirmed in macrophages from beta-hexosaminidase knockout mice. beta-Hexosaminidase is characterized as a peptidoglycan hydrolase that exerts its mycobactericidal effect at the macrophage plasma membrane during mycobacteria-induced secretion of lysosomes Mus musculus
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S2 cell
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 Drosophila melanogaster
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information HEXO2 Is important for limiting growth of Mycobacterium marinum in S2 cells. HEXO2 isoform is sufficient to control bacterial growth in S2 cells Drosophila melanogaster ?
-
 ?
additional information HEXO2 Is important for limiting growth of Mycobacterium marinum in S2 cells. HEXO2 isoform is sufficient to control bacterial growth in S2 cells Mus musculus ?
-
 ?

Synonyms

Synonyms Comment Organism
beta-hexosaminidase
-
 Mus musculus
HEXO2
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 Drosophila melanogaster