Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-(hydroxymethyl)-5-methylpyrrolidine-3,4-diol | competitive or uncompetitive inhibition, Ki: 0.004-26 mM, depending on conformation | Bos taurus | |
2-methyltetrahydro-2H-pyran-3,4-diol | uncompetitive inhibition, Ki: 23 mM | Bos taurus | |
2-phenyl-tetrahydro-2H-pyran-3,4-diol | uncompetitive inhibition, Ki: 22-83 mM, depending on conformation | Bos taurus | |
4-hydroxy-2-methyltetrahydro-2H-pyran-3-yl acetate | competitive inhibition, Ki: 0.09 mM | Bos taurus | |
5-(hydroxymethyl)pyrrolidine-2,3,4-triol | competitive inhibition, Ki: 0.91 mM | Bos taurus | |
alpha-L-fucose | competitive inhibition, Ki: 0.3 mM | Bos taurus | |
D-1-deoxymannojirimycin | competitive inhibition, Ki: 0.03 mM | Bos taurus | |
D-1-deoxyrhamnojirimycin | competitive inhibition, Ki: 0.011 mM | Bos taurus | |
D-1-deoxytalonojirimycin | competitive inhibition, Ki: 0.053 mM | Bos taurus | |
D-fucal | uncompetitive inhibition, Ki: 35 mM | Bos taurus | |
L-1-deoxyfuconojirimycin | competitive inhibition, Ki: 0.00003 mM | Bos taurus | |
L-1-deoxymannojirimycin | competitive inhibition, Ki: 90 mM | Bos taurus | |
L-1-deoxyrhamnojirimycin | competitive inhibition, Ki: 1 mM | Bos taurus | |
L-fucal | competitive inhibition, best inhibitor of glycal compounds tested, Ki: 0.05 mM | Bos taurus | |
phenol | noncompetitive inhibition, Ki: 112 mM | Bos taurus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
bovine | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
kidney | - |
Bos taurus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-nitrophenyl-alpha-L-fucopyranoside + H2O | - |
Bos taurus | 4-nitrophenol + alpha-L-fucose | - |
? |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00003 | - |
L-1-deoxyfuconojirimycin | competitive inhibition | Bos taurus | |
0.004 | 26 | 2-(hydroxymethyl)-5-methylpyrrolidine-3,4-diol | competitive or uncompetitive inhibition, depending on conformation | Bos taurus | |
0.011 | - |
D-1-deoxyrhamnojirimycin | competitive inhibition | Bos taurus | |
0.03 | - |
D-1-deoxymannojirimycin | competitive inhibition | Bos taurus | |
0.05 | - |
L-fucal | competitive inhibition, best inhibitor of glycal compounds tested | Bos taurus | |
0.053 | - |
D-1-deoxytalonojirimycin | competitive inhibition | Bos taurus | |
0.09 | - |
4-hydroxy-2-methyltetrahydro-2H-pyran-3-yl acetate | competitive inhibition | Bos taurus | |
0.91 | - |
5-(hydroxymethyl)pyrrolidine-2,3,4-triol | competitive inhibition | Bos taurus | |
1 | - |
L-1-deoxyrhamnojirimycin | competitive inhibition | Bos taurus | |
22 | 83 | 2-phenyl-tetrahydro-2H-pyran-3,4-diol | uncompetitive inhibition, depending on conformation | Bos taurus | |
23 | - |
2-methyltetrahydro-2H-pyran-3,4-diol | uncompetitive inhibition | Bos taurus | |
35 | - |
D-fucal | uncompetitive inhibition | Bos taurus | |
90 | - |
L-1-deoxymannojirimycin | competitive inhibition | Bos taurus | |
112 | - |
phenol | noncompetitive inhibition | Bos taurus |