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Literature summary for 3.2.1.46 extracted from

  • Hanada, E.; Suzuki, K.
    Activation of human brain galactosylceramidase by phosphatidylserine (1979), Biochim. Biophys. Acta, 575, 410-420.
    View publication on PubMed
Search for more literature for 3.2.1.46

Activating Compound

Activating Compound Comment Organism Structure
phosphatidylserine in absence of sodium taurocholate Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.1
-
 galactosylceramide taurocholate activated Homo sapiens
0.2
-
 galactosylceramide phosphatidylserine activated Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
D-galactosyl-N-acylsphingosine + H2O Homo sapiens
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partially Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
D-galactosyl-N-acylsphingosine + H2O
-
 Homo sapiens D-galactose + N-acylsphingosine
-
 ?
D-galactosyl-N-acylsphingosine + H2O
-
 Homo sapiens ?
-
 ?
galactocerebroside + H2O
-
 Homo sapiens D-galactose + N-acylceramide
-
 ?
galactosylceramide + H2O
-
 Homo sapiens D-galactose + N-acylceramide
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
4.2
-
 taurocholate activated Homo sapiens
4.7
-
 phosphatidylserine activated Homo sapiens

pH Range

pH Minimum pH Maximum Comment Organism
3.5 6
-
 Homo sapiens