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BRENDA support

Literature summary for 3.2.1.45 extracted from

  • Salvioli, R.; Tatti, M.; Ciaffoni, F.; Vaccaro, A.M.
    Further studies on the reconstitution of glucosylceramidase activity by Sap C and anionic phospholipids (2000), FEBS Lett., 472, 17-21.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
additional information The reconstruction of the activity of lysosomal enzyme requires phospholipids and a protein factor: saposin C. The hydrophobic properties of saposin C are regulated by the pH of the environment. The interaction of saposin C with membranes is affected by the content of anionic phospholipids Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
placenta
-
Homo sapiens
-