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Literature summary for 3.2.1.45 extracted from

  • Brady, R.O.; Kanfer, J.; Shapiro, D.
    The metabolism of glucocerebrosides (1965), J. Biol. Chem., 240, 39-43.
    View publication on PubMed
Search for more literature for 3.2.1.45

General Stability

General Stability Organism
dialysis, stable to Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
p-hydroxymercuribenzoate weak Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
glucocerebroside + H2O Homo sapiens
-
 glucose + ceramide
-
 ?
glucocerebroside + H2O Rattus norvegicus
-
 glucose + ceramide
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
spleen
-
 Homo sapiens
-
spleen
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3-O-benzoyl-N-stearylglucosphingosine + H2O not: galactocerebroside Homo sapiens D-glucose + 3-O-benzoyl-N-stearylsphingosine
-
 ?
3-O-benzoyl-N-stearylglucosphingosine + H2O not: galactocerebroside Rattus norvegicus D-glucose + 3-O-benzoyl-N-stearylsphingosine
-
 ?
glucocerebroside + H2O
-
 Homo sapiens glucose + ceramide
-
 ?
glucocerebroside + H2O
-
 Rattus norvegicus glucose + ceramide
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6
-
-
 Homo sapiens

pH Range

pH Minimum pH Maximum Comment Organism
5 8 pH 5.0: about 70% of maximum activity, pH 8.0: about 30% of maximum activity Homo sapiens