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Literature summary for 3.2.1.35 extracted from

  • Wang, X.Y.; Tan, J.X.; Vasse, M.; Delpech, B.; Ren, G.S.
    Comparison of hyaluronidase expression, invasiveness and tubule formation promotion in ER (-) and ER (+) breast cancer cell lines in vitro (2009), Chin. Med. Sci., 122, 1300-1304.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
breast cancer cell
-
Homo sapiens
-
HBL-100 cell
-
Homo sapiens
-
MCF-7 cell
-
Homo sapiens
-
MDA-MB-231 cell
-
Homo sapiens
-
MDA-MB-435 cell
-
Homo sapiens
-
MDA-MB-435S cell
-
Homo sapiens
-
MDA-MB-453 cell
-
Homo sapiens
-
SK-BR-3 cell
-
Homo sapiens
-
T-47D cell
-
Homo sapiens
-
ZR-75 cell
-
Homo sapiens
-
ZR-75-30 cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
hyaluronan + 2 H2O
-
Homo sapiens N-acetyl-beta-D-glucosamine + D-glucuronate + ?
-
?

Synonyms

Synonyms Comment Organism
hyaluronidase
-
Homo sapiens
HYase
-
Homo sapiens

Expression

Organism Comment Expression
Homo sapiens estrogen receptor(-) breast cancer cells secrete significantly more hyaluronidase than estrogen receptor(+) breast cancer cells up