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Literature summary for 3.2.1.35 extracted from

  • Kimura, M.; Kim, E.; Kang, W.; Yamashita, M.; Saigo, M.; Yamazaki, T.; Nakanishi, T.; Kashiwabara, S.; Baba, T.
    Functional roles of mouse sperm hyaluronidases, HYAL5 and SPAM1, in fertilization (2009), Biol. Reprod., 81, 939-947.
    View publication on PubMed
Search for more literature for 3.2.1.35

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
52000
-
 SPAM1 Mus musculus
55000
-
 HYAL5 Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
hyaluronan + 2 H2O Mus musculus
-
 N-acetyl-beta-D-glucosamine + D-glucuronate + ?
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
sperm
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
hyaluronan + 2 H2O
-
 Mus musculus N-acetyl-beta-D-glucosamine + D-glucuronate + ?
-
 ?

Synonyms

Synonyms Comment Organism
HYAL5
-
 Mus musculus
hyaluronidase-5
-
 Mus musculus
SPAM1
-
 Mus musculus

General Information

General Information Comment Organism
malfunction HYAL5-deficient epididymal sperm is functionally normal, the loss of SPAM1 results in a remarkably increased accumulation of sperm on the surface or outer edge of the cumulus Mus musculus
physiological function SPAM1 is involved in sperm penetration through the cumulus matrix Mus musculus