Cloned (Comment) | Organism |
---|---|
precursor from venom gland, DNA and amino acid sequence determination and analysis, phylogenetic analysis and sequence comparisons, functional expression of His-tagged enzyme in insect cells, but not in Escherichia coli, and secretion of the recombinant enzyme, overview | Synanceia horrida |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
extracellular | venom | Synanceia horrida | - |
- |
intracellular | venom gland enzyme | Synanceia horrida | 5622 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Synanceia horrida | Q801Z8 | stonefish | - |
Posttranslational Modification | Comment | Organism |
---|---|---|
glycoprotein | the enzyme contains three potential N-glycosylation sites | Synanceia horrida |
proteolytic modification | the precursor enzyme contains a signal sequence for targeting into endoplasmic reticulum | Synanceia horrida |
Purification (Comment) | Organism |
---|---|
native enzyme from lyophilized venom by affinity chromatography | Synanceia horrida |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
hyaluronic acid hexasaccharide + H2O = hyaluronic acid disaccharide + hyaluronic acid tetrasaccharide | the enzyme contains four hyaluronan binding sites [B(X)7B] | Synanceia horrida |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
venom | - |
Synanceia horrida | - |
venom gland | precursor | Synanceia horrida | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
hyaluronan + H2O | human substrate | Synanceia horrida | hyaluronan oligomers | - |
? |
Synonyms | Comment | Organism |
---|---|---|
hyaluronidase | - |
Synanceia horrida |
SFHYA1 | - |
Synanceia horrida |