Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-mercaptoethanol | - |
Macaca sp. | |
DTT | - |
Macaca sp. |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | inner acrosomal membrane | Macaca sp. | 16020 | - |
plasma membrane | cell surface | Macaca sp. | 5886 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
64000 | - |
x * 64000, SDS-PAGE | Macaca sp. |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
hyaluronic acid-rich cumulus matrix + H2O | Macaca sp. | investment of oocyte during sperm invasion | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Macaca sp. | - |
6 isozymes in sperm | - |
Posttranslational Modification | Comment | Organism |
---|---|---|
glycoprotein | N-glycosylation is absolutely necessary for activity, deglycosylation leads to complete loss of activity, enzyme binds to lectins Con A, LEL, STL, PHA-e, Jacalin, and PSA, mannose is the major sugar within and at the terminal sequence of the glycans | Macaca sp. |
Purification (Comment) | Organism |
---|---|
from sperm surface by treatment with phosphatidylinositol-specific phospholipase C | Macaca sp. |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
sperm | - |
Macaca sp. | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
hyaluronic acid-rich cumulus matrix + H2O | - |
Macaca sp. | ? | - |
? | |
hyaluronic acid-rich cumulus matrix + H2O | investment of oocyte during sperm invasion | Macaca sp. | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 64000, SDS-PAGE | Macaca sp. |
Synonyms | Comment | Organism |
---|---|---|
hyaluronidase | - |
Macaca sp. |
PH-20 | - |
Macaca sp. |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Macaca sp. |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7 | - |
assay at | Macaca sp. |
Organism | Comment | pI Value Maximum | pI Value |
---|---|---|---|
Macaca sp. | isoelectric focusing, 6 isoforms | - |
5.1 |