Literature summary for 3.2.1.23 extracted from

Cagnoni, A.J.; Uhrig, M.L.; Varela, O.
Synthesis of pentopyranosyl-containing thiodisaccharides. Inhibitory activity against beta-glycosidases (2009), Bioorg. Med. Chem., 17, 6203-6212.

Search for more literature for 3.2.1.23

Inhibitors

Inhibitors	Comment	Organism	Structure
benzyl 3-deoxy-4-S-(beta-D-galactopyranosyl)-4-thio-beta-D-erythro-pentopyranoside	non-competitive inhibitor	Escherichia coli
benzyl 3-deoxy-4-S-(beta-D-galactopyranosyl)-4-thio-beta-D-threo-pentopyranoside	mixed-type inhibitor	Escherichia coli
additional information	not inhibited by 2-propyl 3-deoxy-4-S-(beta-D-xylopyranosyl)-4-thio-alpha-D-xylohexopyranoside and 2-propyl 3-deoxy-4-S-(beta-D-xylopyranosyl)-4-thio-alpha-D-lyxohexopyranoside	Escherichia coli

Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2-nitrophenyl beta-D-galactopyranoside + H2O	-	Escherichia coli	2-nitrophenol + beta-D-galactose	-	?

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
0.032	-	benzyl 3-deoxy-4-S-(beta-D-galactopyranosyl)-4-thio-beta-D-threo-pentopyranoside	in sodium phosphate buffer (100 mM, pH 7.3, MgCl2 1.2 mM, beta-mercaptoethanol 100 mM)	Escherichia coli
0.8	-	benzyl 3-deoxy-4-S-(beta-D-galactopyranosyl)-4-thio-beta-D-erythro-pentopyranoside	in sodium phosphate buffer (100 mM, pH 7.3, MgCl2 1.2 mM, beta-mercaptoethanol 100 mM)	Escherichia coli

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Release 2023.1 (January 2023)