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Literature summary for 3.2.1.23 extracted from
- Specific determination of beta-galactocerebrosidase activity via competitive inhibition of beta-galactosidase (2009), Clin. Chem., 55, 541-548.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| AgNO3 | competitive inhibitor | Mus musculus |  |
| FeCl3 | - |
Mus musculus | |
| HgCl2 | - |
Mus musculus | |
| ZnCl2 | - |
Mus musculus | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.363 | - |
4-methylumbelliferyl-beta-D-galactopyranoside | without inhibitor | Mus musculus | |
| 4.94 | - |
4-methylumbelliferyl-beta-D-galactopyranoside | in presence of inhibitor | Mus musculus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| lysosome | - |
Mus musculus | 5764 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 120000 | - |
subunit C, gel filtration chromatography | Mus musculus |
| 400000 | - |
subunit B, gel filtration chromatography | Mus musculus |
| 520000 | - |
subunit A, gel filtration chromatography | Mus musculus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
twi +/i C57BL6 mice | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| hematopoietic stem cell | - |
Mus musculus | - |
| neural stem cell | precursor cell | Mus musculus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
30.3 mU/mg, hematopoetic stem cells | Mus musculus |
| additional information | - |
8.75 mU/mg, neural presursor cells | Mus musculus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4-methylumbelliferyl-beta-D-galactopyranoside + H2O | pH 4.0, 30 min, 37°C | Mus musculus | 4-methylumbelliferone + beta-D-galactopyranose | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| beta-gal | - |
Mus musculus |
| beta-galactosidase | - |
Mus musculus |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.00012 | - |
AgNO3 | - |
Mus musculus | |
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Release 2023.1 (January 2023)
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