Literature summary for 3.2.1.23 extracted from

Shaw, G.C.; Kao, H.S.; Chiou, C.Y.
Cloning, expression, and catabolite repression of a gene encoding beta-galactosidase of Bacillus megaterium ATCC 14581 (1998), J. Bacteriol., 180, 4734-4738.

Search for more literature for 3.2.1.23

Activating Compound

Activating Compound	Comment	Organism	Structure
additional information	the enzyme expression is highly induced by lactose but not by isopropyl-beta-D-thiogalactopyranoside, IPTG	Priestia megaterium

Cloned(Commentary)

Cloned (Comment)	Organism
gene mbgA, DNA and amino acid sequence determination and anaylsis, genetic organization, a 27-bp inverted repeat overlaps the mbgA promoter sequence, and is a target for catabolite repressors, expression in Escherichia coli strain JM109	Priestia megaterium

Protein Variants

Protein Variants	Comment	Organism
additional information	disruption of gene mbgA in the bacterial chromosome results in loss of lactose-inducible beta-galactosidase production, base substitutions within two partially overlapping catabolite-responsive elements CRE-I and/or CRE-II cause partial relief from catabolite repression	Priestia megaterium

Inhibitors

Inhibitors	Comment	Organism	Structure
additional information	the enzyme is subject to catabolite repression by D-glucose	Priestia megaterium

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
118088	-	x * 118088, sequence calculation	Priestia megaterium

Organism

Organism	UniProt	Comment	Textmining
Priestia megaterium	O85167	strain ATCC 14581, gene mbgA	-

Subunits

Subunits	Comment	Organism
?	x * 118088, sequence calculation	Priestia megaterium

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Release 2023.1 (January 2023)