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Literature summary for 3.2.1.20 extracted from

  • Adisakwattana, S.; Chantarasinlapin, P.; Thammarat, H.; Yibchok-Anun, S.
    A series of cinnamic acid derivatives and their inhibitory activity on intestinal alpha-glucosidase (2009), J. Enzyme Inhib. Med. Chem., 24, 1194-1200.
    View publication on PubMed
Search for more literature for 3.2.1.20

Inhibitors

Inhibitors Comment Organism Structure
caffeic acid
-
 Rattus norvegicus
ferulic acid
-
 Rattus norvegicus
isoferulic acid
-
 Rattus norvegicus
m-hydroxycinnamic acid
-
 Rattus norvegicus
o-hydroxycinnamic acid
-
 Rattus norvegicus
p-hydroxycinnamic acid
-
 Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
intestine
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
maltose + H2O assay at pH 6.9, 37°C, reaction stopped by suspension of the mixtures in boiling water for 10 min Rattus norvegicus 2 D-glucose
-
 ?
sucrose + H2O assay at pH 6.9, 37°C, reaction stopped by suspension of the mixtures in boiling water for 10 min Rattus norvegicus D-glucose + D-fructose
-
 ?

Synonyms

Synonyms Comment Organism
alpha-glucosidase
-
 Rattus norvegicus

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.45
-
 substrate sucrose Rattus norvegicus ferulic acid
0.45
-
 substrate sucrose Rattus norvegicus isoferulic acid
0.49
-
 substrate sucrose Rattus norvegicus caffeic acid
0.74
-
 substrate maltose Rattus norvegicus caffeic acid
0.76
-
 substrate maltose Rattus norvegicus isoferulic acid
0.79
-
 substrate maltose Rattus norvegicus ferulic acid