Literature summary for 3.2.1.20 extracted from

Yoshida, K.; Hishida, A.; Iida, O.; Hosokawa, K.; Kawabata, J.
Flavonol caffeoylglycosides as alpha-glucosidase inhibitors from Spiraea cantoniensis flower (2008), J. Agric. Food Chem., 56, 4367-4371.

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Application

Application	Comment	Organism
medicine	inhibitors from Spiraea cantoniensis could be physiologically useful for treatment of diabetes	Rattus norvegicus

Inhibitors

Inhibitors	Comment	Organism	Structure
kaempferol 3-O-(6-O-caffeoyl)-beta-D-galactoside	flavonol caffeoylglycoside from Spiraea cantoniensis flower	Rattus norvegicus
kaempferol 3-O-(6-O-caffeoyl)-beta-D-glucoside	flavonol caffeoylglycoside from Spiraea cantoniensis flower	Rattus norvegicus
quercetin 3-O-(6-O-caffeoyl)-beta-D-galactoside	flavonol caffeoylglycoside from Spiraea cantoniensis flower	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
intestine	-	Rattus norvegicus	-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
additional information	-	shows specific activity of 0.70 U/ml	Rattus norvegicus

Synonyms

Synonyms	Comment	Organism
alpha-glucosidase	-	Rattus norvegicus
maltase	-	Rattus norvegicus

IC50 Value

IC50 Value	IC50 Value Maximum	Comment	Organism	Inhibitor	Structure
0.085	-	-	Rattus norvegicus	quercetin 3-O-(6-O-caffeoyl)-beta-D-galactoside
0.35	-	-	Rattus norvegicus	kaempferol 3-O-(6-O-caffeoyl)-beta-D-galactoside
0.47	-	-	Rattus norvegicus	kaempferol 3-O-(6-O-caffeoyl)-beta-D-glucoside

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Release 2023.1 (January 2023)