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Literature summary for 3.2.1.18 extracted from

  • Yoshizumi, S.; Suzuki, S.; Hirai, M.; Hinokio, Y.; Yamada, T.; Yamada, T.; Tsunoda, U.; Aburatani, H.; Yamaguchi, K.; Miyagi, T.; Oka, Y.
    Increased hepatic expression of ganglioside-specific sialidase, NEU3, improves insulin sensitivity and glucose tolerance in mice (2007), Metab. Clin. Exp., 56, 420-429.
    View publication on PubMed
Search for more literature for 3.2.1.18

Cloned(Commentary)

Cloned (Comment) Organism
adenoviral-mediated gene transfer is used to overexpress hNeu3 in the livers of male mice. hepatic Neu3 overexpression improves insulin sensitivity and glucose tolerance through modification of ganglioside composition and peroxisome proliferator-activated receptor gamma signaling Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
plasma membrane asssociated Homo sapiens 5886
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens sialidase-3 is a key enzyme for ganglioside hydrolysis. Neu3 is an important regulator of insulin sensitivity and glucose tolerance ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens Q9UQ49
-
-

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information sialidase-3 is a key enzyme for ganglioside hydrolysis. Neu3 is an important regulator of insulin sensitivity and glucose tolerance Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
Ganglioside sialidase
-
 Homo sapiens
Membrane sialidase
-
 Homo sapiens
N-acetyl-alpha-neuraminidase 3
-
 Homo sapiens
sialidase-3
-
 Homo sapiens