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Literature summary for 3.2.1.18 extracted from
- Effects of inorganic anions on the activation of acid sialidases (2003), Biol. Pharm. Bull., 26, 295-298.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| additional information | the enzyme is activated at 37°C and acidic pH, activation is dependent on time, pH and temperature, activation is inhibited by amastatin | Homo sapiens | |
| additional information | the enzyme is activated at 37°C and acidic pH, activation is dependent on time, pH and temperature, activation is not inhibited by amastatin | Sus scrofa |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Br- | activates | Homo sapiens |  |
| Br- | activates | Sus scrofa | |
| Cl- | activates up to 1 M | Homo sapiens | |
| Cl- | activates up to 100 mM, above 100 mM chloride inhibits the enzyme | Sus scrofa | |
| additional information | not affected by nitrate, sulfate, sulfite, and disulfite ions | Sus scrofa | |
| NO3- | activates | Homo sapiens | |
| S2O42- | activates | Homo sapiens | |
| SO32- | activates | Homo sapiens | |
| SO42- | activates | Homo sapiens | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
| Sus scrofa | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| partial | Sus scrofa |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Sus scrofa | - |
| placenta | - |
Homo sapiens | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| acid sialidase | - |
Homo sapiens |
| acid sialidase | - |
Sus scrofa |
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