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Literature summary for 3.2.1.18 extracted from
- Renal neuraminidase: characterization in normal rat kidney and measurement in experimentally induced nephrotic syndrome (1986), Biochem. J., 239, 705-710.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| alpha-D-N-acetylneuraminic acid | - |
Rattus norvegicus |  |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.2 | - |
4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid | glomeruli | Rattus norvegicus | |
| 0.23 | - |
4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid | cortex | Rattus norvegicus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| kidney | - |
Rattus norvegicus | - |
| liver | - |
Rattus norvegicus | - |
Storage Stability
| Storage Stability | Organism |
|---|---|
| -20°C | Rattus norvegicus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid + H2O | - |
Rattus norvegicus | 4-methylumbelliferone + N-acetylneuraminic acid | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 4.4 | - |
- |
Rattus norvegicus |
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Release 2023.1 (January 2023)
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