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Literature summary for 3.2.1.147 extracted from

  • Scofield, A.M.; Rossiter, J.T.; Witham, P.; Kite, G.C.; Nash, R.J.; Fellows, E.
    Inhibition of thioglucosidase-catalysed glucosinolate hydrolysis by castanospermine and related alkaloids (1990), Phytochemistry, 29, 107-109.
No PubMed abstract available

Inhibitors

Inhibitors Comment Organism Structure
(2R,5R)-dihydroxymethyl-(3R,4R)-dihydroxypyrrolidine inhibition of hydrolysis of sinigrin and progoitrin at pH 5 and at pH 7 Brevicoryne brassicae
(2R,5R)-dihydroxymethyl-(3R,4R)-dihydroxypyrrolidine
-
Sinapis sp.
1,4-dideoxy-1,4-imino-D-arabinitol inhibition of hydrolysis of progoitrin at pH 5 in citrate buffer and at pH 7 in phosphate buffer, inhibition of hydrolysis of sinigrin at pH 7 in phosphate buffer, no hydrolysis of progoitrin and sinigrin at pH 5 in acetate buffer Brevicoryne brassicae
1-deoxynojirimycin inhibition of hydrolysis of progoitrin at pH 5 in citrate buffer and at pH 7 in phosphate buffer, inhibition of hydrolysis of sinigrin at pH 7 in phosphate buffer, no hydrolysis of progoitrin and sinigrin at pH 5 in acetate buffer Brevicoryne brassicae
alexine inhibition of hydrolysis of progoitrin at pH 5 and at pH 7, inhibition of hydrolysis of sinigrin at pH 7, no inhibition of hydrolysis of sinigrin at pH 5 Brevicoryne brassicae
castanospermine
-
Brevicoryne brassicae
castanospermine
-
Sinapis sp.

Organism

Organism UniProt Comment Textmining
Brevicoryne brassicae
-
i.e. cabbage aphid
-
Sinapis sp.
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
muscle of head and thorax Brevicoryne brassicae
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
progoitrin + H2O
-
Brevicoryne brassicae additional information
-
?
sinigrin + H2O
-
Brevicoryne brassicae D-glucose + 3-isothiocyanatoprop-1-ene + SO42-
-
?
sinigrin + H2O
-
Sinapis sp. D-glucose + 3-isothiocyanatoprop-1-ene + SO42-
-
?