Protein Variants | Comment | Organism |
---|---|---|
D77N/D78N | mutation abolishes the hydrolytic activity on O-acetyl-ADP-ribose | Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | required for hydrolysis of O-acetyl-ADP-ribose | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
isoform ARH3 | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2'-O-acetyl-ADP-ribose + H2O | rate of hydrolysis by isoform ARH3 is 250fold that observed with isoform ARH1, isoform ARH2 is inactive with this substrate | Homo sapiens | ADP-ribose + acetate | - |
? |