Literature summary for 3.2.1.143 extracted from

Tanuma, S.i.; Sakagami, H.; Endo, H.
Inhibitory effect of tannin on poly(ADP-rinbose) glycohydrolase (1989), Biochem. Int., 18, 701-708.

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Inhibitors

Inhibitors	Comment	Organism	Structure
gallic acid	0.1 mg/ml, 9% inhibition	Homo sapiens
galloylgallic acid	0.1 mg/ml, 11% inhibition	Homo sapiens
glucuronic acid	0.1 mg/ml, 14% inhibition	Homo sapiens
tannin	0.01 mg/ml, 89% inhibition, competitive with respect to poly(ADP-ribose)	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
placenta	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
poly(ADP-ribose)n + H2O	-	Homo sapiens	ADP-ribose	-	?

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Release 2023.1 (January 2023)