Any feedback?
Literature summary for 3.2.1.143 extracted from
- Purification of poly(ADP-ribose) glycohydrolase detection of its isoforms by a zymogram following one- or two-dimensional electrophoresis (1994), Anal. Biochem., 218, 265-272.
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 60000 | - |
x * 60000, poly(ADP-ribose) glycohydrolase G1, G2 and G3, SDS-PAGE | Bos taurus |
| 74000 | - |
x * 74000, poly(ADP-ribose) glycohydrolase G4, SDS-PAGE | Bos taurus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| poly(ADP-ribose)n + H2O | Bos taurus | the enzyme is responsible for the catabolism of poly(ADP-ribose), the enzyme is a crucial determinant of polymer metabolism which is known to be implicated in DNA repair and other cellular processes | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
calf | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| 4 poly(ADP-ribose) glycohydrolase isoforms: G1, G2, G3, G4 | Bos taurus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| thymus | - |
Bos taurus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 69.95 | - |
- |
Bos taurus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| poly(ADP-ribose)n + H2O | - |
Bos taurus | ADP-ribose | - |
? | |
| poly(ADP-ribose)n + H2O | the enzyme is responsible for the catabolism of poly(ADP-ribose), the enzyme is a crucial determinant of polymer metabolism which is known to be implicated in DNA repair and other cellular processes | Bos taurus | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 74000, poly(ADP-ribose) glycohydrolase G4, SDS-PAGE | Bos taurus |
| ? | x * 60000, poly(ADP-ribose) glycohydrolase G1, G2 and G3, SDS-PAGE | Bos taurus |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PARG | - |
Bos taurus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
