Literature summary for 3.2.1.141 extracted from

Carpinelli, J.; Kraemer, R.; Agosin, E.
Metabolic engineering of Corynebacterium glutamicum for trehalose overproduction: role of the TreYZ trehalose biosynthetic pathway (2006), Appl. Environ. Microbiol., 72, 1949-1955.

Search for more literature for 3.2.1.141

Application

Application	Comment	Organism
food industry	trehalose has many potential applications in biotechnology and the food industry due to its protective effect against environmental stress. Raising trehalose productivity can be achieved through homologous overexpression of maltooligosyltrehalose synthase and maltooligosyltrehalose trehalohydrolase. Overexpression of the treY gene and the treY/treZ synthetic operon significantly increases maltooligosyltrehalose synthase activity, the rate-limiting step, and improves the specific productivity and the final titer of trehalose. Furthermore, a strong decrease is noted in glycogen accumulation. Expression of galU/treY and galU/treYZ synthetic operons show a partial recovery in the intracellular glycogen levels and a significant improvement in both intra- and extracellular trehalose content	Corynebacterium glutamicum

Cloned(Commentary)

Cloned (Comment)	Organism
overexpression of the treZ gene and the treY/treZ synthetic operon	Corynebacterium glutamicum

Organism

Organism	UniProt	Comment	Textmining
Corynebacterium glutamicum	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
maltoheptaosyltrehalose + H2O	-	Corynebacterium glutamicum	maltoheptaose + alpha,alpha'-trehalose	-	?

Synonyms

Synonyms	Comment	Organism
Maltooligosyl trehalose trehalohydrolase	-	Corynebacterium glutamicum
TreZ	-	Corynebacterium glutamicum

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)