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Literature summary for 3.2.1.130 extracted from
- Endomannosidase processes oligosaccharides of alpha1-antitrypsin and its naturally occurring genetic variants in the Golgi apparatus (2006), Cell. Mol. Life Sci., 63, 1923-1932.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| subcloned into the expression vector pcDNA6/myc-His, overexpression in clone 9 cells and castanospermine-treated hepatocytes | Rattus norvegicus |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| Golgi apparatus | in pre-Golgi intermediates | Rattus norvegicus | 5794 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | Q5GF25 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| BRL-3A cell | - |
Rattus norvegicus | - |
| additional information | clone 9 hepatocyte | Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| human alpha1-antitrypsin + H2O | acts on both native and misfolded variants of alpha1-antitrypsin, establishing its function as a Golgi apparatus-located back-up mechanism for protein N-glycosylation | Rattus norvegicus | ? | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| endomannosidase | - |
Rattus norvegicus |
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Release 2023.1 (January 2023)
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