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Literature summary for 3.2.1.114 extracted from

  • Petersen, L.; Ardevol, A.; Rovira, C.; Reilly, P.J.
    Molecular mechanism of the glycosylation step catalyzed by Golgi alpha-mannosidase II: a QM/MM metadynamics investigation (2010), J. Am. Chem. Soc., 132, 8291-8300.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
gluco-hydroxyiminolactam
-
Drosophila melanogaster
mannoimidazole
-
Drosophila melanogaster
swainsonine most powerful inhibitor Drosophila melanogaster

Metals/Ions

Metals/Ions Comment Organism Structure
Zn2+ contains zinc Drosophila melanogaster

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
GlcNAcMan5GlcNAc2 + H2O Drosophila melanogaster
-
? + alpha-D-mannose
-
?

Organism

Organism UniProt Comment Textmining
Drosophila melanogaster Q24451
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GlcNAcMan5GlcNAc2 + H2O
-
Drosophila melanogaster ? + alpha-D-mannose
-
?

Synonyms

Synonyms Comment Organism
GmII
-
Drosophila melanogaster
Golgi alpha-mannosidase II
-
Drosophila melanogaster