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Literature summary for 3.2.1.113 extracted from

  • Tremblay, L.O.; Nagy Kovacs, E.; Daniels, E.; Wong, N.K.; Sutton-Smith, M.; Morris, H.R.; Dell, A.; Marcinkiewicz, E.; Seidah, N.G.; McKerlie, C.; Herscovics, A.
    Respiratory distress and neonatal lethality in mice lacking Golgi alpha1,2-mannosidase IB involved in N-glycan maturation (2007), J. Biol. Chem., 282, 2558-2566.
    View publication on PubMed
Search for more literature for 3.2.1.113

Protein Variants

Protein Variants Comment Organism
additional information alpha1,2-mannosidase IB null mice (-/-). Null mice with normal gross appearance at birth, but they display respiratory distress and die within a few hours with evident lung hemorrhage. Demonstrates the specific role of Golgi alpha1,2-mannosidase IB in pulmonary function and development. Histological comparison of lungs from wild type (+/+) and alpha1,2-mannosidase IB null mice (-/-) Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
Golgi apparatus
-
 Mus musculus 5794
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Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
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Mus musculus P39098 Golgi alpha1,2-mannosidase IB
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Mus musculus P45700 Golgi alpha1,2-mannosidase IA
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Purification (Commentary)

Purification (Comment) Organism
-
 Mus musculus

Source Tissue

Source Tissue Comment Organism Textmining
central nervous system In situ hybridization shows high levels of alpha1,2-mannosidase IB Mus musculus
-
cerebellum levels of Golgi alpha1,2-mannosidase IC are similar in most tissues, with the exception of placenta and liver Mus musculus
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gut In situ hybridization shows high levels of alpha1,2-mannosidase IA Mus musculus
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gut In situ hybridization shows high levels of alpha1,2-mannosidase IB Mus musculus
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intestine Golgi alpha1,2-mannosidase IA Mus musculus
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kidney Golgi alpha1,2-mannosidase IA Mus musculus
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kidney In situ hybridization shows high levels of alpha1,2-mannosidase IB Mus musculus
-
kidney levels of Golgi alpha1,2-mannosidase IC are similar in most tissues, with the exception of placenta and liver Mus musculus
-
liver Golgi alpha1,2-mannosidase IA Mus musculus
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liver In situ hybridization shows high levels of alpha1,2-mannosidase IA Mus musculus
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lung Golgi alpha1,2-mannosidase I displays distinct developmental and tissue-specific expression. Expression of Golgi alpha 1,2-mannosidases (IA, IB, IC) investigated by Nothern blot analysis and in situ hybridization Mus musculus
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lung Golgi alpha1,2-mannosidase I displays distinct developmental and tissue-specific expression. Expression of Golgi alpha 1,2-mannosidases (IA, IB, IC) investigated by Nothern blot analysis and in situ hybridization. In situ hybridization shows high levels of alpha1,2-mannosidase IB Mus musculus
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lung Golgi alpha1,2-mannosidase I displays distinct developmental and tissue-specific expression. Expression of Golgi alpha 1,2-mannosidases (IA, IB, IC) investigated by Nothern blot analysis and in situ hydridization Mus musculus
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placenta Golgi alpha1,2-mannosidase IA Mus musculus
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placenta Golgi alpha1,2-mannosidase IB Mus musculus
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spleen Golgi alpha1,2-mannosidase IA Mus musculus
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spleen In situ hybridization shows high levels of alpha1,2-mannosidase IB Mus musculus
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stomach Golgi alpha1,2-mannosidase IA Mus musculus
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testis Golgi alpha1,2-mannosidase IB Mus musculus
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thymus Golgi alpha1,2-mannosidase IA Mus musculus
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thymus In situ hybridization shows high levels of alpha1,2-mannosidase IA Mus musculus
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thymus In situ hybridization shows high levels of alpha1,2-mannosidase IB, Golgi alpha1,2-mannosidase IB Mus musculus
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uterus Golgi alpha1,2-mannosidase IA Mus musculus
-
uterus Golgi alpha1,2-mannosidase IB Mus musculus
-

Synonyms

Synonyms Comment Organism
Golgi alpha1,2-mannosidase IA
-
 Mus musculus
Golgi alpha1,2-mannosidase IB
-
 Mus musculus
Golgi alpha1,2-mannosidase IC
-
 Mus musculus