Any feedback?
Literature summary for 3.2.1.10 extracted from
- A fully active, two-active-site, single-chain sucrase-isomaltase from pig small intestine. Implications for the biosynthesis of a mammalian integral stalked membrane protein (1980), J. Biol. Chem., 255, 11332-11338.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| chymotrypsin | almost 25% of palatinase activity after incubation with 0.1 mg/ml for 30 min | Sus scrofa | |
| Elastase | almost 50% of palatinase activity after incubation with 0.1 mg/ml for 30 min | Sus scrofa | |
| Trypsin | almost 25% of palatinase activity after incubation with 0.1 mg/ml for 30 min | Sus scrofa |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 140000 | 150000 | SDS-PAGE, intact pancreatic duct, 2 polypeptide chains, 140000 + 150000 | Sus scrofa |
| 150000 | - |
isomaltase in ileum, SDS-PAGE | Sus scrofa |
| 260000 | - |
SDS-PAGE, pancreas disconnected from duodenum, single polypeptide chain | Sus scrofa |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Sus scrofa | - |
- |
- |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| proteolytic modification | extracellular proteolysis of single-chain pro-sucrase-isomaltase | Sus scrofa |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Sus scrofa |
Reaction
| Reaction | Comment | Organism | Reaction ID |
|---|---|---|---|
| alpha-D-glucopyranosyl-(1-4)-[alpha-D-glucopyranosyl-(1-6)]-alpha-D-glucopyranosyl-(1-4)-alpha-D-glucopyranosyl-(1-4)-alpha-D-glucopyranose + H2O = alpha-D-glucopyranosyl-(1-4)-alpha-D-glucopyranosyl-(1-4)-alpha-D-glucopyranosyl-(1-4)-alpha-D-glucopyranose + D-glucose | enzyme from intestinal mucosa also catalyzes the reaction of sucrase alpha-glucosidase, EC 3.2.1.48 | Sus scrofa |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| small intestine | ileum | Sus scrofa | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| maltose + H2O | - |
Sus scrofa | 2 D-glucose | - |
? |  |
| palatinose + H2O | - |
Sus scrofa | D-glucose + fructose | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| sucrase-isomaltase | consisting of two polypeptid chains | Sus scrofa |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
