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Literature summary for 3.2.1.1 extracted from
- Further studies on the structural differences between the isoenzymes of human parotid alpha-amylase (1971), Biochemistry, 10, 4867-4874.
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 56133 | - |
1 * 56133, isoenzymes of family B, SDS-PAGE | Homo sapiens |
| 61856 | - |
1 * 61856, isoenzymes of family A, SDS-PAGE | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| glycoprotein | isoenzymes of family A are glycoproteins, isoenzymes of family B are not. The carbohydrate moiety of family A contains 6 mol of glucosamine, 3 mol of fucose, 2 mol of mannose and 2 mol of galactose per mol of enzyme, no sialic acid detected | Homo sapiens |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| parotid gland | two families of isoenzymes: family A comprising isoenzymes 5, 3 and 1 and family B, comprising isoenzymes 4 and 2 | Homo sapiens | - |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| monomer | 1 * 61856, isoenzymes of family A, SDS-PAGE | Homo sapiens |
| monomer | 1 * 56133, isoenzymes of family B, SDS-PAGE | Homo sapiens |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 45 | - |
90 min, about 15% loss of activity of isoenzymes of family A and B | Homo sapiens |
| 55 | - |
30 min, about 80% loss of the activity of isoenzymes A and B, complete inactivation after 90 min | Homo sapiens |
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Release 2023.1 (January 2023)
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