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Literature summary for 3.13.2.3 extracted from

  • Eustaquio, A.; Haerle, J.; Noel, J.; Moore, B.
    S-adenosyl-L-methionine hydrolase (adenosine-forming), a conserved bacterial and archeal protein related to SAM-dependent halogenases (2008), ChemBioChem, 9, 2215-2219 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.13.2.3

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli BL21(DE3) cells Salinispora arenicola

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0016
-
 S-adenosyl-L-methionine at pH 7.9 and 37°C Salinispora arenicola

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-adenosyl-L-methionine + H2O Salinispora arenicola
-
 adenosine + L-methionine
-
 ir
S-adenosyl-L-methionine + H2O Salinispora arenicola CNS-205
-
 adenosine + L-methionine
-
 ir

Organism

Organism UniProt Comment Textmining
Salinispora arenicola
-
-
-
Salinispora arenicola CNS-205
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Salinispora arenicola

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme has very slow reversible iodinase activity in vitro Salinispora arenicola ?
-
 ?
additional information the enzyme has very slow reversible iodinase activity in vitro Salinispora arenicola CNS-205 ?
-
 ?
S-adenosyl-L-methionine + H2O
-
 Salinispora arenicola adenosine + L-methionine
-
 ir
S-adenosyl-L-methionine + H2O
-
 Salinispora arenicola CNS-205 adenosine + L-methionine
-
 ir

Synonyms

Synonyms Comment Organism
duf62
-
 Salinispora arenicola
SAM-hydrolase (adenosine-forming)
-
 Salinispora arenicola

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.0077
-
 S-adenosyl-L-methionine at pH 7.9 and 37°C Salinispora arenicola

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8
-
-
 Salinispora arenicola