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Literature summary for 3.1.99.B2 extracted from
- An archaeal endonuclease displays key properties of both eukaryal XPF-ERCC1 and Mus81 (2005), J. Biol. Chem., 280, 5924-5928.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Saccharolobus solfataricus | Q7LXL5 | - |
- |
| Saccharolobus solfataricus P2 | Q7LXL5 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | the best substrate is a 3' flap followed by a nicked duplex, nicked three-way junctions, and nicked fourway junctions. The efficient cleavage of a nicked duplex substrate demonstrates that no single-stranded flap is required, rather a discontinuity in the DNA duplex is enough to promote the nuclease activity | Saccharolobus solfataricus | ? | - |
? |  |
| additional information | the best substrate is a 3' flap followed by a nicked duplex, nicked three-way junctions, and nicked fourway junctions. The efficient cleavage of a nicked duplex substrate demonstrates that no single-stranded flap is required, rather a discontinuity in the DNA duplex is enough to promote the nuclease activity | Saccharolobus solfataricus P2 | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| XPF endonuclease | - |
Saccharolobus solfataricus |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 55 | - |
assay at | Saccharolobus solfataricus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.6 | - |
assay at | Saccharolobus solfataricus |
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Release 2023.1 (January 2023)
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