Localization | Comment | Organism | GeneOntology No. | Textmining |
---|
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | substrate recognition and binding, orientation of the flaps into nucleosomes is important for the cleavage, patterns, detailed overview. However, flaps within nucleosomes containing the high-affinity 601 DNA sequence are completely resistant to FEN1 cleavage regardless of orientation. Flaps within such high-affinity nucleosome binding sequences will require ATP-dependent remodeling activity for completion of base excision repair | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | substrate recognition and binding, orientation of the flaps into nucleosomes is important for the cleavage, patterns, detailed overview. However, flaps within nucleosomes containing the high-affinity 601 DNA sequence are completely resistant to FEN1 cleavage regardless of orientation. Flaps within such high-affinity nucleosome binding sequences will require ATP-dependent remodeling activity for completion of base excision repair | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
FEN1 endonuclease | - |
Homo sapiens |