Application | Comment | Organism |
---|---|---|
degradation | enzyme catalyse the hydrolysis of toxic organophosphorus cholinesterase-inhibiting compounds, including pesticides and chemical nerve agents | Alteromonas sp. |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | - |
Alteromonas sp. |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Alteromonas sp. | - |
JD6.5, halophilic bacterium | - |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
diisopropyl fluorophosphate + H2O = diisopropyl phosphate + fluoride | enzyme exhibits stereoselectivity toward the chiral phosphorus center of the p-nitrophenyl analogs of sarin and soman | Alteromonas sp. |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
O-cyclohexylmethylphosphonofluoridate + H2O | i.e. GF | Alteromonas sp. | ? | - |
? | |
paraoxon + H2O | i.e. diethyl-4-nitrophenyl phosphate, poor substrate | Alteromonas sp. | diethylphosphate + 4-nitrophenol | - |
? | |
sarin + H2O | substrates are also p-nitrophenyl analogs of sarin, the enzyme exhibits a stereoselective preference for the R-P-enantiomers of sarin | Alteromonas sp. | ? | - |
? | |
soman + H2O | substrates are also p-nitrophenyl analogs of soman, the enzyme exhibits a stereoselective preference for the R-P-enantiomers of soman | Alteromonas sp. | ? | - |
? |