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Literature summary for 3.1.8.2 extracted from

  • Hoskin, F.C.G.; Prusch, R.D.
    Characterization of a DFP-hydrolyzing enzyme in squid posterior salivary gland by use of Soman, DFP and manganous ion (1983), comp. Biochem. Physiol. C, 75, 17-20.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
Mn2+ weak Loligo sp.
Mn2+ activates Rattus norvegicus

Metals/Ions

Metals/Ions Comment Organism Structure
Mn2+ activation Rattus norvegicus
Mn2+ not Loligo sp.
Mn2+ 0.4 mM Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Loligo sp.
-
-
-
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
Rattus norvegicus
-
nerve
-
Loligo sp.
-
salivary gland posterior, higher activity in glands of female than male squid Loligo sp.
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
diisopropyl fluorophosphate + H2O best substrate of squid enzyme Loligo sp. diisopropyl phosphate + fluoride
-
?
diisopropyl fluorophosphate + H2O at about 5-10% of soman hydrolysis Rattus norvegicus diisopropyl phosphate + fluoride
-
?
diisopropyl fluorophosphate + H2O i.e. DFP Rattus norvegicus diisopropyl phosphate + fluoride
-
?
diisopropyl fluorophosphate + H2O i.e. DFP Loligo sp. diisopropyl phosphate + fluoride
-
?
soman + H2O best substrate Rattus norvegicus ?
-
?
soman + H2O 10-20% the rate of diisopropyl fluorophosphate hydrolysis Loligo sp. ?
-
?