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Literature summary for 3.1.8.1 extracted from

  • Abd-Allah, G.M.; Mariee, A.D.
    Nitrite-mediated inactivation of human plasma paraoxonase-1: possible beneficial effect of aromatic amino acids (2008), Appl. Biochem. Biotechnol., 150, 281-288.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
nitrite 1 mM nitrite inhibits 23% of PON-1 activity, while 6 mM represses 85% of the enzyme activity, the inhibition of PON-1 activity by nitrite is significantly reduced by tryptophan, reduced glutathione, and catalase additions Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P27169
-
-

Source Tissue

Source Tissue Comment Organism Textmining
blood plasma
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
paraoxon + H2O
-
Homo sapiens diethylphosphate + 4-nitrophenol
-
?

Synonyms

Synonyms Comment Organism
paraoxonase-1
-
Homo sapiens
PON-1
-
Homo sapiens