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Literature summary for 3.1.8.1 extracted from
- Evidence that several conserved histidine residues are required for hydrolytic activity of human paraoxonase/arylesterase (1999), Chem. Biol. Interact., 119-120, 235-241.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| H114N | catalytically inactive | Homo sapiens |
| H133N | catalytically inactive | Homo sapiens |
| H284N | catalytically inactive | Homo sapiens |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| diethyldicarbonate | - |
Homo sapiens |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
PON1 type Q | - |
Reaction
| Reaction | Comment | Organism | Reaction ID |
|---|---|---|---|
| an aryl dialkyl phosphate + H2O = dialkyl phosphate + an aryl alcohol | mechanism | Homo sapiens |
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Release 2023.1 (January 2023)
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