Any feedback?
Literature summary for 3.1.6.19 extracted from
- Highly enantioselective sec-alkyl sulfatase activity of Sulfolobus acidocaldarius DSM 639 (2004), Org. Lett., 6, 5009-5010.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Sulfolobus acidocaldarius | - |
- |
- |
| Sulfolobus acidocaldarius DSM 639 | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| (2R)-octan-2-yl sulfate + H2O | hydrolysis of (R)-enantiomers from the racemate provided the corresponding (S)-configured sec-alcohols. Excellent enantioselectivity is observed for octan-2-yl sulfate. When the sulfate ester moiety is gradually moved toward the center of the molecule (octan-3-yl sulfate and octan-4-yl sulfate), the enantioselectivities decreases, which is due to the fact that the alkyl groups flanking the sulfate ester group became similar in size, thus making the chiral recognition process more difficult | Sulfolobus acidocaldarius | (2S)-octan-2-ol + sulfate | - |
? |  |
| (2R)-octan-2-yl sulfate + H2O | hydrolysis of (R)-enantiomers from the racemate provided the corresponding (S)-configured sec-alcohols. Excellent enantioselectivity is observed for octan-2-yl sulfate. When the sulfate ester moiety is gradually moved toward the center of the molecule (octan-3-yl sulfate and octan-4-yl sulfate), the enantioselectivities decreases, which is due to the fact that the alkyl groups flanking the sulfate ester group became similar in size, thus making the chiral recognition process more difficult | Sulfolobus acidocaldarius DSM 639 | (2S)-octan-2-ol + sulfate | - |
? | |
| (2S)-1-phenylpropan-2-yl sulfate + H2O | - |
Sulfolobus acidocaldarius | (2S)-1-phenylpropan-2-ol + sulfate | - |
? | |
| (2S)-1-phenylpropan-2-yl sulfate + H2O | - |
Sulfolobus acidocaldarius DSM 639 | (2S)-1-phenylpropan-2-ol + sulfate | - |
? | |
| rac-octan-3-yl sulfate + H2O | hydrolysis of (R)-enantiomers from the racemate provided the corresponding (S)-configured sec-alcohols. Excellent enantioselectivity is observed for octan-2-yl sulfate. When the sulfate ester moiety is gradually moved toward the center of the molecule (octan-3-yl sulfate and octan-4-yl sulfate), the enantioselectivities decreases, which is due to the fact that the alkyl groups flanking the sulfate ester group became similar in size, thus making the chiral recognition process more difficult | Sulfolobus acidocaldarius | (3S)-octan-3-ol + sulfate | - |
? | |
| rac-octan-3-yl sulfate + H2O | hydrolysis of (R)-enantiomers from the racemate provided the corresponding (S)-configured sec-alcohols. Excellent enantioselectivity is observed for octan-2-yl sulfate. When the sulfate ester moiety is gradually moved toward the center of the molecule (octan-3-yl sulfate and octan-4-yl sulfate), the enantioselectivities decreases, which is due to the fact that the alkyl groups flanking the sulfate ester group became similar in size, thus making the chiral recognition process more difficult | Sulfolobus acidocaldarius DSM 639 | (3S)-octan-3-ol + sulfate | - |
? | |
| rac-octan-4-yl sulfate + H2O | hydrolysis of (R)-enantiomers from the racemate provides the corresponding (S)-configured sec-alcohols. Excellent enantioselectivity is observed for octan-2-yl sulfate. When the sulfate ester moiety is gradually moved toward the center of the molecule (octan-3-yl- and octan-4-yl sulfate), the enantioselectivities decreases, which is due to the fact that the alkyl groups flanking the sulfate ester group became similar in size, thus making the chiral recognition process more difficult | Sulfolobus acidocaldarius | (4S)-octan-4-ol + sulfate | - |
? | |
| rac-octan-4-yl sulfate + H2O | hydrolysis of (R)-enantiomers from the racemate provides the corresponding (S)-configured sec-alcohols. Excellent enantioselectivity is observed for octan-2-yl sulfate. When the sulfate ester moiety is gradually moved toward the center of the molecule (octan-3-yl- and octan-4-yl sulfate), the enantioselectivities decreases, which is due to the fact that the alkyl groups flanking the sulfate ester group became similar in size, thus making the chiral recognition process more difficult | Sulfolobus acidocaldarius DSM 639 | (4S)-octan-4-ol + sulfate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| (R)-specific sec-alkylsulfatase | - |
Sulfolobus acidocaldarius |
| sec-alkylsulfatase | - |
Sulfolobus acidocaldarius |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 22 | - |
assay at | Sulfolobus acidocaldarius |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 2 | 3 | assay at | Sulfolobus acidocaldarius |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
