General Stability | Organism |
---|---|
in water rapid loss of activity | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
chondroitin 4-sulfate | at 0.1 mM | Homo sapiens | |
chondroitin 6-sulfate | at 0.1 mM | Homo sapiens | |
Cl- | - |
Homo sapiens | |
heparan sulfate | - |
Homo sapiens | |
NaCl | due to Cl- | Homo sapiens | |
phosphate | - |
Homo sapiens | |
SO42- | organic sulfates | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0115 | - |
O-(alpha-L-idopyranosyluronic acid 2-sulfate)-(1-4)-2,5-anhydro-D-mannitol 6-sulfate | pool 1 from urine | Homo sapiens | |
0.013 | - |
O-(alpha-L-idopyranosyluronic acid 2-sulfate)-(1-4)-2,5-anhydro-D-mannitol 6-sulfate | pool 2 in urine | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
lysosome | - |
Homo sapiens | 5764 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
95000 | - |
- |
Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
dermatan sulfate + H2O | Homo sapiens | - |
dermatan + sulfate | - |
? | |
heparan sulfate + H2O | Homo sapiens | - |
dermatan + sulfate | - |
? | |
heparin + H2O | Homo sapiens | - |
desulfated heparin + sulfate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
urine | - |
Homo sapiens | - |
Storage Stability | Organism |
---|---|
-20°C, neutral pH, for one year or more | Homo sapiens |
4°C, pH 7.2, 150 mM NaCl, several days | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
dermatan sulfate + H2O | - |
Homo sapiens | dermatan + sulfate | - |
? | |
heparan sulfate + H2O | - |
Homo sapiens | dermatan + sulfate | - |
? | |
heparin + H2O | - |
Homo sapiens | desulfated heparin + sulfate | - |
? | |
O-(alpha-L-idopyranosyluronic acid 2-sulfate)-(1-4)-2,5-anhydro-D-mannitol 6-sulfate + H2O | - |
Homo sapiens | O-(alpha-L-idopyranosyluronic acid)-(1-4)-2,5-anhydro-D-mannitol 6-sulfate + sulfate | - |
? |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
50 | - |
stable for 10 min | Homo sapiens |
75 | - |
2 min, complete loss of activity | Homo sapiens |