Cloned (Comment) | Organism |
---|---|
mutants are expressed in COS-7 cells | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
C447F | mutant shows very low level of activity, the expressed mutation significantly reduces the amount of mature protein, the ARSB mutation has a significant effect on enzyme activity, protein processing and mRNA stability | Homo sapiens |
G308R | mutant shows very low level of activity, the expressed mutation significantly reduces the amount of mature protein, the ARSB mutation has a significant effect on enzyme activity, protein processing and mRNA stability | Homo sapiens |
L472P | mutant shows very low level of activity, the expressed mutation significantly reduces the amount of mature protein, the ARSB mutation has a significant effect on enzyme activity, protein processing and mRNA stability | Homo sapiens |
L82R | mutant shows very low level of activity, the expressed mutation significantly reduces the amount of mature protein, the ARSB mutation has a significant effect on enzyme activity, protein processing and mRNA stability | Homo sapiens |
P313A | mutant shows very low level of activity, the expressed mutation significantly reduces the amount of mature protein, the ARSB mutation has a significant effect on enzyme activity, protein processing and mRNA stability | Homo sapiens |
S240F | mutant shows very low level of activity, the expressed mutation significantly reduces the amount of mature protein, the ARSB mutation has a significant effect on enzyme activity, protein processing and mRNA stability | Homo sapiens |
Y138C | mutant shows very low level of activity, the expressed mutation significantly reduces the amount of mature protein, the ARSB mutation has a significant effect on enzyme activity, protein processing and mRNA stability | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
lysosome | - |
Homo sapiens | 5764 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-nitrocatechol sulfate + H2O | - |
Homo sapiens | 4-nitrocatechol + sulfate | - |
? | |
dermatan sulfate + H2O | - |
Homo sapiens | dermatan + sulfate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
4-sulfatase | - |
Homo sapiens |
ARSB | - |
Homo sapiens |
arylsulfatase B | - |
Homo sapiens |
N-acetylgalactosamine-4-sulfatase | - |
Homo sapiens |