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Literature summary for 3.1.4.53 extracted from

  • Lynex, C.N.; Li, Z.; Chen, M.L.; Toh, K.Y.; Low, R.W.; Goh, D.L.; Tay, S.K.
    Identification and molecular characterization of a novel PDE4D11 cAMP-specific phosphodiesterase isoform (2008), Cell. Signal., 20, 2247-2255.
    View publication on PubMed
Search for more literature for 3.1.4.53

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Neuro-2A and NIH-3T3 cells Mus musculus

Inhibitors

Inhibitors Comment Organism Structure
IBMX non-selective PDE inhibitor Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Mus musculus 5829
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
79030
-
 calculated from amino acid sequence Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus B1PSD9
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain in the brain, PDE4D11 expression levels increase in the cerebellum, but decrease in the hippocampus with progressive age Mus musculus
-
brain stem
-
 Mus musculus
-
cerebellum PDE4D11 expression levels increase in the cerebellum with progressive age Mus musculus
-
cerebrum
-
 Mus musculus
-
heart lowest expression in heart Mus musculus
-
hippocampus PDE4D11 expression levels decrease in the hippocampus with progressive age Mus musculus
-
kidney
-
 Mus musculus
-
liver highest expression level Mus musculus
-
lung
-
 Mus musculus
-
olfactory bulb
-
 Mus musculus
-
spleen highest expression level Mus musculus
-
testis
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3',5'-cAMP + H2O
-
 Mus musculus 5'-AMP
-
 ?

Synonyms

Synonyms Comment Organism
cAMP-specific phosphodiesterase 4D11
-
 Mus musculus
PDE4D11 isoform Mus musculus