Cloned (Comment) | Organism |
---|---|
expression of the catalytic domain in Escherichia coli | Homo sapiens |
Crystallization (Comment) | Organism |
---|---|
catalytic domain of inactive mutant D201N in complex with substrate cAMP at 1.56 A resolution. Q369 forms only one hydrogen bond ith the adenine of cAMP. Structural comparison between isoform PDE4D2-cAMP and PDE10A2-cAMP shows an anti configuration of cAMP in PDE4, but syn in PDE10 | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
isoform PDE4D2 | - |