Application | Comment | Organism |
---|---|---|
molecular biology | development of cell-permeable peptide reagents based upon the N-terminal region of PDE4D5 that allow for the selective disruption of PDE4D5 targeting to specific signalling scaffolds, namely beta-arrestin and RACK1 | Homo sapiens |
Crystallization (Comment) | Organism |
---|---|
NMR and CD analysis of the N-terminal 38mer peptide of isoform PDE4D5 which contains the entire signaling scaffold protein RACK1 interaction domain together with a portion of the beta-arrestin binding site. The peptiode has a distinct amphipathic helical structure. Study on binding to RACK1 and to beta-arrestin | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
isoform PDE4D5 | - |
Homo sapiens | Q08499 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HEK-293B2 cell | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
cAMP-specific phosphodiesterase-4D5 | - |
Homo sapiens |
PDE4D5 | - |
Homo sapiens |