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Literature summary for 3.1.4.4 extracted from

  • Varadharaj, S.; Steinhour, E.; Hunter, M.G.; Watkins, T.; Baran, C.P.; Magalang, U.; Kuppusamy, P.; Zweier, J.L.; Marsh, C.B.; Natarajan, V.; Parinandi, N.L.
    Vitamin C-induced activation of phospholipase D in lung microvascular endothelial cells: Regulation by MAP kinases (2006), Cell. Signal., 18, 1396-1407.
    View publication on PubMed
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Activating Compound

Activating Compound Comment Organism Structure
vitamin C at pharmacological doses activates PLD in the lung microvascular endothelial cells through oxidative stress and activation of mitogen-activated protein kinase Bos taurus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Bos taurus vitamin C at pharmacological doses activates PLD in the lung microvascular endothelial cells through oxidative stress and activation of mitogen-activated protein kinase ?
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 ?

Organism

Organism UniProt Comment Textmining
Bos taurus
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Source Tissue

Source Tissue Comment Organism Textmining
endothelial cell lung microvascular Bos taurus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information vitamin C at pharmacological doses activates PLD in the lung microvascular endothelial cells through oxidative stress and activation of mitogen-activated protein kinase Bos taurus ?
-
 ?