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Literature summary for 3.1.4.37 extracted from

  • Baburina, Y.L.; Gordeeva, A.E.; Moshkov, D.A.; Krestinina, O.V.; Azarashvili, A.A.; Odinokova, I.V.; Azarashvili, T.S.
    Interaction of myelin basic protein and 2',3'-cyclic nucleotide phosphodiesterase with mitochondria (2014), Biochemistry (Moscow), 79, 555-565.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
Rattus norvegicus 16020
-
mitochondrion distribution of isozymes in mitochondrial fractions, i.e. myelin fraction, synaptic and nonsynaptic mitochondria, obtained after separation of brain mitochondria Rattus norvegicus 5739
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
46000
-
x * 46000, SDS-PAGE Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
nucleoside 2',3'-cyclic phosphate + H2O Rattus norvegicus
-
nucleoside 2'-phosphate
-
?
nucleoside 2',3'-cyclic phosphate + H2O Rattus norvegicus Wistar
-
nucleoside 2'-phosphate
-
?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-
Rattus norvegicus Wistar
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
Rattus norvegicus
-
liver
-
Rattus norvegicus
-
myelin
-
Rattus norvegicus
-
oligodendrocyte
-
Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
nucleoside 2',3'-cyclic phosphate + H2O
-
Rattus norvegicus nucleoside 2'-phosphate
-
?
nucleoside 2',3'-cyclic phosphate + H2O
-
Rattus norvegicus Wistar nucleoside 2'-phosphate
-
?

Subunits

Subunits Comment Organism
? x * 46000, SDS-PAGE Rattus norvegicus

Synonyms

Synonyms Comment Organism
2',3'-cyclic nucleotide 3'-phosphodiesterase
-
Rattus norvegicus
2',3'-cyclic nucleotide phosphodiesterase
-
Rattus norvegicus

General Information

General Information Comment Organism
physiological function the enzyme is involved in regulation of the nonspecific pore, addition of myelin fraction associated with brain mitochondria to the suspension of liver mitochondria can lead to binding of the enzyme and myelin basic protein, present in the fraction with liver mitochondria under the conditions of both closed and opened permeability transition pore Rattus norvegicus