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Literature summary for 3.1.4.37 extracted from

  • Kanno, T.; Kurotaki, T.; Yamada, N.; Yamashita, K.; Wako, Y.; Tsuchitani, M.
    Activity of 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase) in spinal cord with spongy change induced by a single oral dose of aniline in rats (2010), Toxicol. Pathol., 38, 359-365.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm along the cytoplasmic boundaries of the normal oligodendroglia. Mild to moderate anti-CNPase staining extends to the swollen cytoplasm of the oligodendroglia in aniline-treated rats from day 2 to day 4 Rattus norvegicus 5737
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Organism

Organism UniProt Comment Textmining
Rattus norvegicus
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three-week-old male Crl:CD (SD) IGS rats
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Source Tissue

Source Tissue Comment Organism Textmining
cerebral white matter
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Rattus norvegicus
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spinal cord
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Rattus norvegicus
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Synonyms

Synonyms Comment Organism
2',3'-cyclic nucleotide 3'-phosphodiesterase
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Rattus norvegicus
CNPase
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Rattus norvegicus

Expression

Organism Comment Expression
Rattus norvegicus after treatment with a single dose of aniline at 1000 mg/kg, spongy change in the spinal cord from day 5, after which CNPase expression decreases remarkably down
Rattus norvegicus after treatment with a single dose of aniline at 1000 mg/kg, expression of CNPase increases from day 2 and peaks on days 3 and 4 up