Application | Comment | Organism |
---|---|---|
medicine | PDE5 inhibitors enhance exogenous and endogenous nitric oxide-mediated relaxation in the rat anococcygeus muscle | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
sildenafil | commercial name Viagra | Rattus norvegicus | |
tadalafil | commercial name Cialis | Rattus norvegicus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
90000 | 99000 | the antibody against PDE5 recognizes a 90000/99000 Da doublet band, SDS-PAGE | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
anococcygeus muscle | higher expression than in corpus cavernosum | Rattus norvegicus | - |
corpus cavernosum | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3',5'-cGMP + H2O | - |
Rattus norvegicus | 5'-GMP | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PDE5 | - |
Rattus norvegicus |
phosphodiesterase 5 | - |
Rattus norvegicus |