Application | Comment | Organism |
---|---|---|
medicine | impaired vascular cGMP signalling contributes to the development of diabetic vascular and cardiac dysfunction, which can be prevented by chronic phosphodiesterase-5 inhibition | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
vardenafil | selective inhibitor of phosphodiesterase-5 | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3',5'-cGMP + H2O | - |
Rattus norvegicus | 5'-GMP | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PDE5 | - |
Rattus norvegicus |
phosphodiesterase-5 | - |
Rattus norvegicus |