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Literature summary for 3.1.4.35 extracted from

  • Song, J.; Guo, L.W.; Muradov, H.; Artemyev, N.O.; Ruoho, A.E.; Markley, J.L.
    Intrinsically disordered gamma-subunit of cGMP phosphodiesterase encodes functionally relevant transient secondary and tertiary structure (2008), Proc. Natl. Acad. Sci. USA, 105, 1505-1510.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
chitin column chromatography Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
retina
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3',5'-cGMP + H2O
-
Homo sapiens 5'-GMP
-
?

Synonyms

Synonyms Comment Organism
cGMP phosphodiesterase 6
-
Homo sapiens
PDE6
-
Homo sapiens
PDEgamma PDE6 inhibitory gamma-subunit, PDEgamma keeps PDE6 inactive by binding tightly to the catalytic alpha,beta-subunits in the dark Homo sapiens