Literature summary for 3.1.4.35 extracted from

White, J.B.; Thompson, W.J.; Pittler, S.J.
Characterization of 3',5' cyclic nucleotide phosphodiesterase activity in Y79 retinoblastoma cells: absence of functional PDE6 (2004), Mol. Vis., 10, 738-749.

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Organism

Organism	UniProt	Comment	Textmining
no activity in Homo sapiens	-	functional PDE6 not detected in Y79 retinoblastoma cells. Attempts to enhance iexpression with cell culture or with introduction of virus expressing PDE6 are not successful. The results indicate that expression of a fully active stable PDE6 enzyme requires other post-transcriptional events that do not occur or are inhibited in Y79 cells	-

Source Tissue

Source Tissue	Comment	Organism	Textmining

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Release 2023.1 (January 2023)