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Literature summary for 3.1.4.35 extracted from

  • Burnett, A.L.
    Phosphodiesterase 5 mechanisms and therapeutic applications (2005), Am. J. Cardiol., 96, 29M-31M.
    View publication on PubMed

Application

Application Comment Organism
medicine phosphodiesterase 5 inhibition is a therapeutic strategy for erectile dysfunction Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3',5'-cGMP + H2O Homo sapiens phosphodiesterase 5 converts the second messenger 3',5'-cGMP to its inactive form guanosine 5'-phosphate
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3',5'-cGMP + H2O phosphodiesterase 5 converts the second messenger 3',5'-cGMP to its inactive form Homo sapiens guanosine 5'-phosphate
-
?

Synonyms

Synonyms Comment Organism
PDE5
-
Homo sapiens
phosphodiesterase 5
-
Homo sapiens